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典型文献
Access to 3-alkylselenindoles by multicomponent reaction of indoles,selenium powder and unactivated alkyl halides under transition-metal-free conditions
文献摘要:
Herein,we reported a convenient and efficient multicomponent reaction of indoles,selenium powder and unactivated alkyl halides.This protocol provides a practical,and facile approach for the synthesis of 3-alkylselenindole derivatives.The advantages of this strategy include mild and transition-metal-free conditions,broad functional group tolerance,the use of simple and easily accessible seleniium powder and alkyl halides as coupling partners.More importantly,the reaction proceeded smoothly with a large scale(>10 g,>90%yield),which further highlighted the potential application of this selenation strategy.
文献关键词:
作者姓名:
Huan Liu;Zhong-Jian Cai;Shun-Jun Ji
作者机构:
Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry,Chemical Engineering and Materials Science&Collaborative Innovation Center of Suzhou Nano Science and Technology,Soochow University,Suzhou 215123,China
引用格式:
[1]Huan Liu;Zhong-Jian Cai;Shun-Jun Ji-.Access to 3-alkylselenindoles by multicomponent reaction of indoles,selenium powder and unactivated alkyl halides under transition-metal-free conditions)[J].中国化学快报(英文版),2022(09):4303-4305
A类:
alkylselenindoles,alkylselenindole,seleniium,selenation
B类:
Access,by,multicomponent,reaction,selenium,powder,unactivated,halides,under,transition,metal,free,conditions,Herein,we,reported,convenient,efficient,This,protocol,provides,practical,facile,approach,synthesis,derivatives,advantages,this,strategy,include,mild,broad,functional,group,tolerance,use,simple,easily,accessible,coupling,partners,More,importantly,proceeded,smoothly,large,scale,yield,which,further,highlighted,potential,application
AB值:
0.555648
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