The development of rice cultivars with improved nitrogen use efficiency(NUE)is desirable for sustain-able agriculture.Achieving this goal depends in part on understanding how rice responds to low soil nitrogen(N)and identifying causative genes underlying this trait.To identify quantitative trait loci(QTL)or genes associated with low N response,we conducted a genome-wide association study(GWAS)using a diverse panel of 230 rice accessions and performed a transcriptomic investigation of rice accessions with differential responses to low N stress at two N levels.We detected 411 GWAS-associated genes in 5 QTL and 2722 differentially expressed genes in response to low N,of which 24 were identified by both methods and ranked according to gene annotations,literature queries,gene expression,and genetic diversity analysis.The large-scale datasets obtained from this study reveal low N-responsive characteristics and provide insights towards understanding the regulatory mechanisms of N-deficiency tolerance in rice,and the candidate genes or QTL would be valuable resources for increasing rice NUE via molecular biotechnology.

Qing Li;Xueli Lu;Changjian Wang;Lan Shen;Liping Dai;Jinli He;Long Yang;Peiyuan Li;Yifeng Hong;Qiang Zhang;Guojun Dong;Jiang Hu;Guangheng Zhang;Deyong Ren;Zhenyu Gao;Longbiao Guo;Qian Qian;Li Zhu;Dali Zeng

State Key Laboratory of Rice Biology,China National Rice Research Institute,Chinese Academy of Agricultural Sciences,Hangzhou 311401,Zhejiang,China

作物学报（英文版）

[1]Qing Li;Xueli Lu;Changjian Wang;Lan Shen;Liping Dai;Jinli He;Long Yang;Peiyuan Li;Yifeng Hong;Qiang Zhang;Guojun Dong;Jiang Hu;Guangheng Zhang;Deyong Ren;Zhenyu Gao;Longbiao Guo;Qian Qian;Li Zhu;Dali Zeng-.Genome-wide association study and transcriptome analysis reveal new QTL and candidate genes for nitrogen-deficiency tolerance in rice)[J].作物学报（英文版）,2022(04):942-951

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