典型文献
Insights into the transition of ductal carcinoma in situ to invasive ductal carcinoma: morphology, molecular portraits, and the tumor microenvironment
文献摘要：
Breast cancer is posing an increasing burden and has become the cancer with the highest incidence among in women in China. The most common histological subtype of breast can-cer is invasive ductal carcinoma (IDC)1,2. Ductal carcinoma in situ (DCIS) is a pre-cancerous lesion that may give rise to IDC. DCIS is a highly heterogeneous group of lesions consisting of 5 main types, which differ in clinical presentation, histo-logic features, biomarker profiles, genetic abnormalities, pro-gression potential, and clinical outcomes. When cancer cells invade through the basal membrane, they acquire the ability to metastasize. This process is usually accompanied by many genetic and epigenetic changes in tumor suppressors and oncogenes.
文献关键词：
中图分类号：
作者姓名：
Weiling Chen;Guimei Wang;Guojun Zhang
作者机构：
Department of Breast-Thyroid-Surgery and Cancer Center,Xiang'An Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen 361101,China;Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer,Xiang'An Hospital of Xiamen University,Xiamen 361101,China;Key Laboratory for Endocrine-Related Cancer Precision Medicine of Xiamen,Xiang'An Hospital of Xiamen University,Xiamen 361101,China;Xiamen Research Center of Clinical Medicine in Breast&Thyroid Cancers,Xiang'An Hospital of Xiamen University,Xiamen 361101,China;Department of Pathology,Xiang'An Hospital of Xiamen University,Xiamen 361101,China
文献出处：
引用格式：
[1]Weiling Chen;Guimei Wang;Guojun Zhang-.Insights into the transition of ductal carcinoma in situ to invasive ductal carcinoma: morphology, molecular portraits, and the tumor microenvironment)[J].癌症生物学与医学（英文版）,2022(10):1487-1495
A类：
metastasize
B类：
Insights,into,transition,ductal,carcinoma,situ,invasive,morphology,molecular,portraits,tumor,microenvironment,Breast,posing,increasing,burden,has,become,highest,incidence,among,women,China,most,common,histological,subtype,breast,IDC,Ductal,DCIS,cancerous,that,may,give,rise,highly,heterogeneous,group,lesions,consisting,main,types,which,differ,clinical,presentation,features,biomarker,profiles,abnormalities,gression,potential,outcomes,When,cells,invade,through,basal,membrane,they,acquire,ability,This,process,usually,accompanied,by,many,epigenetic,changes,suppressors,oncogenes
AB值：
0.649808
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
