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典型文献
The emerging role of long noncoding RNA RMRP in cancer development and targeted therapy
文献摘要:
The RNA component of mitochondrial RNA-processing endoribonuclease (RMRP) was first described as an entity that cleaved mitochondrial RNA at a priming site of mito-chondrial DNA replication. This long noncoding RNA (lncRNA) was encoded by an evolutionarily conserved nuclear gene that has been characterized in many species, including human, mouse, cattle, zebrafish, toad, and yeast. It was soon learned that RMRP as a component of the RNase MRP complex was also located in the nucleus, and was crit-ical for ribosomal RNA (rRNA) processing, particularly the biosynthesis of 5.8S rRNAs.
文献关键词:
作者姓名:
Qian Hao;Xiang Zhou
作者机构:
Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences,Fudan University,Shanghai 200032,China;Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China;Key Laboratory of Breast Cancer in Shanghai,Fudan University Shanghai Cancer Center,Fudan University,Shanghai 200032,China;Shanghai Key Laboratory of Medical Epigenetics,International Co-laboratory of Medical Epigenetics and Metabolism(Ministry of Science and Technology),Institutes of Biomedical Sciences,Fudan University,Shanghai 200032,China
引用格式:
[1]Qian Hao;Xiang Zhou-.The emerging role of long noncoding RNA RMRP in cancer development and targeted therapy)[J].癌症生物学与医学(英文版),2022(02):140-146
A类:
RMRP,endoribonuclease
B类:
emerging,role,long,noncoding,cancer,development,targeted,therapy,component,mitochondrial,processing,was,first,described,entity,that,cleaved,priming,site,replication,This,lncRNA,encoded,by,evolutionarily,conserved,nuclear,gene,has,been,characterized,many,species,including,human,mouse,cattle,zebrafish,toad,yeast,It,soon,learned,RNase,complex,also,located,nucleus,crit,ical,ribosomal,particularly,biosynthesis,8S,rRNAs
AB值:
0.609783
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