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典型文献
Onset and Recurrence Characteristics of Chinese Patients with Noncardiogenic Ischemic Stroke in Chinese Medicine Hospitals
文献摘要:
Objective:To delineate the onset and recurrence characteristics of noncardiogenic ischemic stroke patients in China.Methods:A prospective,multicenter and registry study was carried out in 2,558 patients at 7 representative clinical sub-centers during November 3,2016 to February 17,2019.A questionnaire was used to collect information of patients regarding CM syndromes and constitutions and associated risk factors.Additionally,stroke recurrence was defined as a primary outcome indicator.Results:A total of 327(12.78%)patients endured recurrence events,1,681(65.72%)patients were men,and the average age was 63.33±9.45 years.Totally 1,741(68.06%)patients suffered first-ever ischemic stroke,1,772(69.27%)patients reported to have hypertension,and 1,640(64.11%)of them reported dyslipidemia,1,595(62.35%)patients exhibited small-artery occlusion by The Trial of Org 10172 in Acute Stroke Treatment(TOAST)classification.Specifically,1,271(49.69%)patients were considered as qi-deficient constitution,and 1,227(47.97%)patients were determined as stagnant blood constitution.There were 1,303(50.94%)patients diagnosed as blood stasis syndrome,1,280(50.04%)patients exhibited phlegm and dampness syndrome and 1,012(39.56%)patients demonstrated qi deficiency syndrome.And 1,033(40.38%)patients declared intracranial artery stenosis,and 478(18.69%)patients reported carotid artery stenosis.The plaque in 1,508(41.36%)patients were of mixed.Particularly,41.09%of them demonstrated abnormal levels of glycated hemoglobin(HbA1c)levels.Conclusions:Recurrence in minor and small-artery stroke cannot be ignored.Hypertension,dyslipidemia,abnormal HbA1c,intracranial artery stenosis and carotid plaque were more common in stroke patients.Particularly,phlegm-dampness and blood stasis syndromes,as well as qi deficiency and blood stasis constitutions,were still the main manifestations of stroke.(Trial registration at ClinicalTrials.gov,No.NCT03174535)
文献关键词:
作者姓名:
GAO Yang;XIE Yan-ming;WANG Gui-qian;CAI Ye-feng;SHEN Xiao-ming;ZHAO De-xi;XIE Ying-zhen;ZHANG Yin;MENG Fan-xing;YU Hai-qing;JIANG Jun-jie;WEI Rui-Li
作者机构:
Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing(100700),China;Department of Rehabilitation,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing(100078),China;Department of Emergency,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing(100010),China;Department of Neurology,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou(510120),China;Department of Neurology,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou(450000),China;Department of Neurology,the Affiliated Hospital of Changchun University of Chinese Medicine,Changchun(130017),China;Department of Neurology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing(100700),China;Department of Neurology,Taiyuan Hospital of Traditional Chinese Medicine,Taiyuan(140107),China
引用格式:
[1]GAO Yang;XIE Yan-ming;WANG Gui-qian;CAI Ye-feng;SHEN Xiao-ming;ZHAO De-xi;XIE Ying-zhen;ZHANG Yin;MENG Fan-xing;YU Hai-qing;JIANG Jun-jie;WEI Rui-Li-.Onset and Recurrence Characteristics of Chinese Patients with Noncardiogenic Ischemic Stroke in Chinese Medicine Hospitals)[J].中国结合医学杂志(英文版),2022(06):492-500
A类:
Noncardiogenic,noncardiogenic,NCT03174535
B类:
Onset,Recurrence,Characteristics,Chinese,Patients,Ischemic,Stroke,Medicine,Hospitals,Objective,delineate,onset,recurrence,characteristics,ischemic,stroke,patients,China,Methods,prospective,multicenter,registry,study,was,carried,representative,clinical,sub,centers,during,November,February,questionnaire,used,collect,information,regarding,CM,syndromes,constitutions,associated,risk,factors,Additionally,defined,primary,outcome,indicator,Results,total,endured,events,were,average,years,Totally,suffered,first,ever,reported,have,hypertension,them,dyslipidemia,exhibited,small,artery,occlusion,by,Org,Acute,Treatment,TOAST,classification,Specifically,considered,qi,deficient,determined,stagnant,blood,There,diagnosed,stasis,phlegm,dampness,demonstrated,deficiency,And,declared,intracranial,stenosis,carotid,plaque,mixed,Particularly,abnormal,levels,glycated,hemoglobin,HbA1c,Conclusions,minor,cannot,ignored,Hypertension,more,common,well,still,main,manifestations,registration,ClinicalTrials,gov
AB值:
0.524601
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