典型文献
Whole-Brain Connectome of GABAergic Neurons in the Mouse Zona Incerta
文献摘要：
The zona incerta(ZI)is involved in various func-tions and may serve as an integrative node of the circuits for global behavioral modulation.However,the long-range connectivity of different sectors in the mouse ZI has not been comprehensively mapped.Here,we obtained whole-brain images of the input and output connections via fluorescence micro-optical sectioning tomography and viral tracing.The principal regions in the input-output circuits of ZI GABAe-rgic neurons were topologically organized.The 3D distribu-tion of cortical inputs showed rostro-caudal correspondence with different ZI sectors,while the projection fibers from ZI sectors were longitudinally organized in the superior collicu-lus.Clustering results show that the medial and lateral ZI are two different major functional compartments,and they can be further divided into more subdomains based on projection and input connectivity.This study provides a comprehen-sive anatomical foundation for understanding how the ZI is involved in integrating different information,conveying motivational states,and modulating global behaviors.
文献关键词：
中图分类号：
作者姓名：
Yang Yang;Tao Jiang;Xueyan Jia;Jing Yuan;Xiangning Li;Hui Gong
作者机构：
Britton Chance Center for Biomedical Photonics,Wuhan National Laboratory for Optoelectronics,MoE Key Laboratory for Biomedical Photonics,Huazhong University of Science and Technology,Wuhan 430074,China;Research Unit of Multimodal Cross Scale Neural Signal Detection and Imaging,Chinese Academy of Medical Sciences,HUST-Suzhou Institute for Brainsmatics,JITRI,Suzhou 215123,China
文献出处：
引用格式：
[1]Yang Yang;Tao Jiang;Xueyan Jia;Jing Yuan;Xiangning Li;Hui Gong-.Whole-Brain Connectome of GABAergic Neurons in the Mouse Zona Incerta)[J].神经科学通报（英文版）,2022(11):1315-1329
A类：
Connectome,Incerta,incerta,GABAe,rgic,rostro,collicu
B类：
Whole,Brain,GABAergic,Neurons,Mouse,Zona,zona,ZI,involved,various,may,serve,integrative,node,circuits,global,behavioral,modulation,However,range,connectivity,different,sectors,mouse,has,not,been,comprehensively,mapped,Here,obtained,whole,brain,images,output,connections,via,fluorescence,micro,optical,sectioning,tomography,viral,tracing,principal,regions,neurons,were,topologically,organized,distribu,cortical,inputs,showed,caudal,correspondence,while,projection,fibers,from,longitudinally,superior,Clustering,results,that,medial,lateral,are,two,major,functional,compartments,they,can,further,divided,into,more,subdomains,This,study,provides,anatomical,foundation,understanding,integrating,information,conveying,motivational,states,modulating,behaviors
AB值：
0.578016
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
