典型文献
Correlation between CD44 and membrane fluidity—a study on biopsies of high-grade serous ovarian tumor
文献摘要：
The functioning of the cell plasma membrane depends on its lipid and protein compositions[1].Changes in membrane physiochem-ical characteristics,such as fluidity,are associated with normal cellular physiology[2]and tumor malignancy[3].As an extensively distributed cell surface marker,CD44 is implicated in the pathogenesis and progression of many cancerous cells,including ovarian cancer cells[4].A previous study on a cell model indicated that the level of CD44 might be correlated with the fluidity of the plasma membrane[5].However,no study has been reported on either the status of plasma membrane fluidity or the levels of CD44 in human tumors.In the present report,we studied the status of membrane fluidity and the level of CD44 in normal ovary epithelium and stage Ⅲ high-grade serous ovarian cancer(HGSOC),a common epithelial ovarian cancer[6].The main methods are described in Supplementary Data.
文献关键词：
中图分类号：
作者姓名：
Jun Shi;Yang Yang;Wei He;Munika Moses;Yi-hua Gu;Ningli Li;Wen Di
作者机构：
Shanghai Institute of Immunology,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;Department of Obstetrics and Gynecology,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200127,China;Shanghai Institute for Biomedical and Pharmaceutical Technologies,Shanghai 200032,China;Department of Pathology,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200127,China;Institut Pasteur of Shanghai,Chinese Academy of Sciences,Shanghai 200031,China
文献出处：
引用格式：
[1]Jun Shi;Yang Yang;Wei He;Munika Moses;Yi-hua Gu;Ningli Li;Wen Di-.Correlation between CD44 and membrane fluidity—a study on biopsies of high-grade serous ovarian tumor)[J].生物化学与生物物理学报（英文版）,2022(12):1928-1930
A类：
physiochem
B类：
Correlation,between,CD44,membrane,fluidity,study,biopsies,high,grade,serous,ovarian,functioning,plasma,depends,its,lipid,protein,compositions,Changes,ical,characteristics,such,are,associated,normal,cellular,physiology,malignancy,extensively,distributed,surface,marker,implicated,pathogenesis,progression,many,cancerous,cells,including,previous,model,indicated,that,might,correlated,However,has,been,reported,either,status,levels,human,tumors,In,present,studied,ovary,epithelium,stage,HGSOC,common,epithelial,main,methods,described,Supplementary,Data
AB值：
0.529299
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