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典型文献
Human umbilical cord mesenchymal stromal cells promote the regeneration of severe endometrial damage in a rat model
文献摘要:
Due to the influence of various social and environmental factors,the incidence of infertility is increasing,and the application of assisted reproductive technology(ART)is becoming more and more wide-spread.At present,the clinical pregnancy rate of in vitro fertilization(IVF)is 40%~60%,and decreased endometrial receptivity is one of the reasons for implantation failure.Endometrial receptivity refers to the capacity of the endometrium to accept embryos.Intrauterine adhesions(IUA),also known as Asherman syndrome(AS),is one of the most common causes of decreased endometrial receptivity after intrauterine surgery or inflammation.At present,most experts be-lieve that IUA should be defined as intrauterine adhesion or fibrosis,which is accompanied by one or more of the following clinical symptoms:menstrual reduction,amenorrhea,repeated abortion,infertility and abnormal placental formation.The treatment of AS needs to restore the structure of the uterine cavity,restore men-struation,and promote the repair and regeneration of fibrosis and dysplasia of the endometrium.Stem cell therapy is becoming a new and effective treatment method to promote the repair and re-generation of the endometrium.
文献关键词:
作者姓名:
Mei Zhuang;Wuwen Zhang;Nuo Cheng;Ling Zhou;Dan Liu;Hua Yan;Ge Fang;Yan Sun;Guoqing Tong
作者机构:
Department of Gynecology,Shanghai Traditional Chinese Medicine Integrated Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200082,China;Reproductive Medicine Center,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Obstetrics and Gynecology,Strategic Support Force Medical Center,Beijing 100101,China;Hospital&Institute of Obstetrics and Gynecology,Fudan University Shanghai Medical College,Shanghai 200011,China
引用格式:
[1]Mei Zhuang;Wuwen Zhang;Nuo Cheng;Ling Zhou;Dan Liu;Hua Yan;Ge Fang;Yan Sun;Guoqing Tong-.Human umbilical cord mesenchymal stromal cells promote the regeneration of severe endometrial damage in a rat model)[J].生物化学与生物物理学报(英文版),2022(01):148-151
A类:
lieve,struation
B类:
Human,umbilical,cord,mesenchymal,stromal,cells,promote,regeneration,severe,endometrial,damage,model,Due,influence,various,social,environmental,factors,incidence,infertility,increasing,application,assisted,reproductive,technology,ART,becoming,more,wide,spread,At,present,clinical,pregnancy,rate,vitro,fertilization,IVF,decreased,receptivity,one,reasons,implantation,failure,Endometrial,refers,capacity,endometrium,accept,embryos,Intrauterine,adhesions,IUA,also,known,Asherman,syndrome,AS,most,common,causes,after,intrauterine,surgery,inflammation,experts,that,should,defined,fibrosis,which,accompanied,by,following,symptoms,menstrual,reduction,amenorrhea,repeated,abortion,abnormal,placental,formation,treatment,needs,restore,structure,cavity,repair,dysplasia,Stem,therapy,new,effective,method
AB值:
0.57945
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