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典型文献
Randomized controlled study of a diagnosis and treatment plan for moderate coronavirus disease 2019 that integrates Traditional Chinese and Western Medicine
文献摘要:
OBJECTIVE:To investigate the clinical efficacy and safety of a diagnosis and treatment plan for moderate coronavirus disease 2019(COVID-19)that integrates traditional Chinese(TCM)and western medicine.METHODS:One hundred twenty patients with moderate COVID-19 were randomized 1:2 to the control group(n=40)and experimental group(n=80).Both groups received conventional western medicine treatment,and the experimental group also received TCM decoction.Over a 2-week period from diagnosis,we observed the time to clinical recovery(TTCR),rate of improvement on lung computed tomography(CT)imaging,time to defervescence,cough remission time,hospital discharge rate,average hospitalization stay,modified Medical Research Council(mMRC)scale score,clinical cure rate,laboratory findings,incidence of progression to severe or critical disease,and adverse events.RESULTS:Among 120 enrolled patients,108 completed the study.The baseline data did not differ between the experimental and control groups(all P>0.05).After treatment,the TTCR,rate of lung CT imaging improvement,time to defervescence,cough remission time,hospital discharge rate,average hospitalization stay(among discharged patients),mMRC scale score,clinical cure rate,and rates of normal values for laboratory findings were better in the experimental group than in the control group(P<0.05 or<0.01).The incidence of progression to severe or critical disease and the incidence of adverse events did not differ between the two groups(P>0.05).CONCLUSION:The diagnosis and treatment plan integrating Chinese and western medicine showed improved clinical efficacy compared with western medicine alone for patients with moderate COVID-19 and is worthy of clinical promotion and application.
文献关键词:
作者姓名:
XIA Wenguang;ZHENG Chanjuan;ZHANG Jixian;HUANG Min;LI Qinglin;DUAN Can;LI Zhengliang;FAN Cunyu;ZOU Yilong;XU Bo;YANG Fengwen;LIU Qingquan
作者机构:
Rehabilitation Department,Hubei Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Wuhan 430000,China;Respiratory Department,Hubei Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Wuhan 430000,China;Endocrinology Department,Hubei Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Wuhan 430000,China;Traditional Chinese Medicine Department,Tianjin University of Traditional Chinese Medicine,Tianjin 300000,China;Emergency Department,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100000,China
引用格式:
[1]XIA Wenguang;ZHENG Chanjuan;ZHANG Jixian;HUANG Min;LI Qinglin;DUAN Can;LI Zhengliang;FAN Cunyu;ZOU Yilong;XU Bo;YANG Fengwen;LIU Qingquan-.Randomized controlled study of a diagnosis and treatment plan for moderate coronavirus disease 2019 that integrates Traditional Chinese and Western Medicine)[J].中医杂志(英文版),2022(02):234-241
A类:
TTCR,defervescence
B类:
Randomized,controlled,study,diagnosis,treatment,plan,moderate,coronavirus,disease,that,integrates,Traditional,Chinese,Medicine,OBJECTIVE,To,investigate,clinical,efficacy,safety,traditional,TCM,western,medicine,METHODS,One,hundred,twenty,patients,were,randomized,experimental,Both,groups,received,conventional,also,decoction,Over,week,period,from,observed,recovery,improvement,lung,computed,tomography,imaging,cough,remission,average,hospitalization,stay,modified,Medical,Research,Council,mMRC,scale,score,cure,laboratory,findings,incidence,progression,severe,critical,adverse,events,RESULTS,Among,enrolled,completed,baseline,data,did,not,differ,between,all,After,among,discharged,normal,values,better,than,two,CONCLUSION,integrating,showed,improved,compared,alone,worthy,promotion,application
AB值:
0.447666
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