典型文献
Hydrophilic phytosterol derivatives:A short review on structural modifications, cholesterol-lowering activity and safety
文献摘要：
Phytosterols have received extensive attention owing to their excellent cholesterol-lowering activity and the role in cardiovascular diseases prevention. However, poor solubility in both oil and water lim-ited the application of free phytosterols in the food industry. Chemical or enzymatic modifications were effective to improve the physicochemical properties as well as the bioavailability and cholesterol-lowering activity of phytosterols. Higher oil solubility and lower melting point of phytosterols have been achieved by esterification and transesterification with fatty acids and triacylglycerols so as to en-hance the bioavailability, reduce formation of precipitates, and improve the sensory quality of products. While the researches on the improvement on its water solubility is a hot topic. Hydrophilic phytosterol derivatives have promising applications in the food industry because most of foods belong to aqueous matrix. Hydrophilic modification is useful and meaningful for phytosterols in both industrial and com-mercial applications. This review mainly highlights the hydrophilic phytosterol derivatives in the fol-lowing aspects: (i) hydrophilic modifications of phytosterols by coupling with various polar components;(ii) cholesterol-lowering activity and possible molecular mechanisms of hydrophilic phy-tosterol derivatives on reducing serum cholesterol level;and (iii) safety evaluation of hydrophilic phy-tosterol derivatives in cell-culture studies, animal models and clinical trials.
文献关键词：
中图分类号：
作者姓名：
Yuyuan Hu;Chuanguo Ma;Xiaowei Chen;Ge Bai;Shujing Guo
作者机构：
College of Food Science and Engineering,Henan University of Technology,Zhengzhou 450001,China
文献出处：
引用格式：
[1]Yuyuan Hu;Chuanguo Ma;Xiaowei Chen;Ge Bai;Shujing Guo-.Hydrophilic phytosterol derivatives:A short review on structural modifications, cholesterol-lowering activity and safety)[J].粮油科技（英文）,2022(03):146-155
A类：
phytosterol,Phytosterols,phytosterols,tosterol
B类：
Hydrophilic,derivatives,short,review,structural,modifications,cholesterol,lowering,activity,safety,have,received,extensive,attention,their,excellent,role,cardiovascular,diseases,prevention,However,poor,solubility,both,oil,water,lim,ited,free,industry,Chemical,enzymatic,were,effective,physicochemical,properties,well,bioavailability,Higher,melting,point,been,achieved,by,transesterification,fatty,acids,triacylglycerols,hance,reduce,formation,precipitates,sensory,quality,products,While,researches,improvement,its,hot,topic,promising,applications,because,most,foods,belong,aqueous,matrix,useful,meaningful,industrial,mercial,This,mainly,highlights,hydrophilic,fol,lowing,aspects,coupling,various,polar,components,possible,molecular,mechanisms,reducing,serum,level,iii,evaluation,culture,studies,animal,models,clinical,trials
AB值：
0.492642
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