典型文献
Examination of Homologies between COVID-19 Vaccines and Common Allergens: The Potential for T Cell-mediated Responses for Allergic Rhinitis and Asthma
文献摘要：
As the SARS-CoV-2 virus shares relatively large protein sequences homologous to grass pollens, dust mites, and molds, our objective was to assess the potential overlap between the COVID-19 mRNA vaccines from Pfizer-BioNtech and Moderna and known allergens. We found 7 common allergens with potential for cross-reactivity with the Pfizer vaccine and 19 with the Moderna vaccine, including common grasses, molds, and dust mites. T-cell mediated antigen cross-reactivity between viruses and allergens is a relatively new area of study in clinical immunology; a discipline that may be particularly useful regarding the SARS-CoV-2 virus and the allergic response in humans. These results suggest that vaccination with the Pfizer-BioNtech and Moderna COVID-19 vaccines may contribute to T-cell cross-reactivity with allergens that impact allergic asthma and allergic rhinitis. Further research should assess the clinical implications of COVID-19 vaccination on the severity and symptomatology of the allergic disease, in addition to natural viral infection.
文献关键词：
Rhinitis, allergic;Allergy;COVID-19;Cross-reactivity;mRNA;Vaccines
中图分类号：
作者姓名：
Hartwell Micah;Greiner Benjamin H.;Nicks Savannah
作者机构：
Oklahoma State University Center for Health Sciences, Department of Psychiatry and Behavioral Sciences, Tulsa, Oklahoma, United States;Oklahoma State University Center for Health Sciences, Office of Medical Student Research, Tulsa, Oklahoma, United States;University of Texas Medical Branch, Department of Internal Medicine, Galveston, Texas, United States
文献出处：
引用格式：
[1]Hartwell Micah;Greiner Benjamin H.;Nicks Savannah-.Examination of Homologies between COVID-19 Vaccines and Common Allergens: The Potential for T Cell-mediated Responses for Allergic Rhinitis and Asthma)[J].感染性疾病和免疫（英文）,2022(04):282-284
A类：
Homologies,Allergens,pollens,BioNtech
B类：
Examination,between,Vaccines,Common,Potential,Cell,mediated,Responses,Allergic,Rhinitis,Asthma,SARS,CoV,shares,relatively,large,protein,sequences,homologous,dust,mites,molds,our,objective,was,assess,potential,overlap,vaccines,from,Pfizer,Moderna,known,allergens,We,found,common,cross,reactivity,including,grasses,cell,antigen,viruses,new,area,study,clinical,immunology,discipline,that,may,particularly,useful,regarding,allergic,response,humans,These,results,suggest,vaccination,contribute,impact,asthma,rhinitis,Further,research,should,implications,severity,symptomatology,disease,addition,natural,viral,infection,Allergy,Cross
AB值：
0.498249
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