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典型文献
Long-term Management of Patients with Myocardial Infarction: An Updated Review
文献摘要:
The outcomes of patients with myocardial infarction (MI) have substantially improved given the rapid progress that has occurred in revascularization techniques and secondary prevention, and the majority of MI patients subsequently enter a chronic stable phase. Therefore, the long-term management of patients with MI has become a core issue in daily clinical practice for cardiologists. The long-term incidence of adverse events can be further reduced using newly developed medications and therapies ranging from lipid-lowering agents (eg, proprotein convertase subtilisin/kexin type 9 inhibitors) to anti-thrombotic treatments (eg, shortened dual anti-platelet therapy). However, a considerable number of patients still experience adverse events, as some residual risk can remain despite intensive secondary prevention, such as continuously elevated cholesterol levels, chronic cardiovascular inflammation, and rapid atherosclerosis progression due to increased plaque instability. Therefore, the present review sought to summarize and discuss recent advances in several key aspects regarding the long-term management of MI patients, with the expectation of clarifying the available treatment strategies for various clinical scenarios, examining the gaps between trial evidence and clinical practice, and providing possible directions for future research.
文献关键词:
Myocardial infarction;Long-term management;Dual anti-platelet therapy;Lipid-lowering treatment;Inflammation;Revascularization
作者姓名:
Chen Runzhen;Zhao Hanjun;Yan Hongbing
作者机构:
Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China;Department of Internal Medicine, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, Guangdong 518038, China;Coronary Heart Disease Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China
引用格式:
[1]Chen Runzhen;Zhao Hanjun;Yan Hongbing-.Long-term Management of Patients with Myocardial Infarction: An Updated Review)[J].心血管病探索(英文),2022(04):241-262
A类:
cardiologists
B类:
Long,term,Management,Patients,Myocardial,Infarction,An,Updated,Review,outcomes,patients,myocardial,infarction,MI,have,substantially,improved,given,rapid,that,occurred,revascularization,techniques,secondary,prevention,majority,subsequently,enter,chronic,stable,phase,Therefore,long,management,become,core,issue,daily,clinical,practice,incidence,adverse,events,can,further,reduced,using,newly,developed,medications,therapies,ranging,from,lipid,lowering,agents,proprotein,convertase,subtilisin,kexin,type,inhibitors,thrombotic,treatments,shortened,platelet,therapy,However,considerable,number,still,experience,some,residual,risk,remain,despite,intensive,such,continuously,elevated,cholesterol,levels,cardiovascular,inflammation,atherosclerosis,progression,due,increased,plaque,instability,present,review,sought,summarize,discuss,recent,advances,several,key,aspects,regarding,expectation,clarifying,available,strategies,various,scenarios,examining,gaps,between,trial,evidence,providing,possible,directions,future,research,Dual,Lipid,Inflammation,Revascularization
AB值:
0.674687
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