Objective:To observe the therapeutic effect of combined scalp and body acupuncture on the motor symp-toms in Parkinson's disease(PD),and on the score of levodopa equivalent dose(LED).Methods:This is a randomized,single blind trial.Sixty-six patients with PD were randomized into an acupuncture+medication group(33 patients)and a medication group(33 patients).The patients were aware of allocation and the assessors were blinded to group assignment and therapeutic regimen.Anti-PD drugs were administered in both groups.In the acupuncture+medication group,scalp and body acupuncture therapy was added.Treatments were applied for 8 weeks.In scalp acupuncture,the ante-rior oblique line of the vertex-temporal(MS6),lateral line 1 of the vertex(MS8),lateral line 2 of the vertex(MS9),and lower-lateral line of the occiput(MS14)were selected.In the body acupuncture,the acupoints included Bǎihuì(百会GV20),Sìshéncōng(四神聪EX-HN1),and Dàzhuī(大椎GV14)),as well as the bilateral Fēngchí(风池GB20)),Nèiguān(内关PC6),Hégǔ(合谷LI4)),Gānshū(肝俞BL18)),Shènshū(肾俞BL23)),Yánglíngquán(阳陵 泉GB34),Zúsānlǐ(足三里ST36),Fēnglóng 丰隆ST40)),Sānyīnjiāo(三 阴交SP6)),Tàixī(太溪KI3),and Tàichōng(太冲LR3).Before and after treatments,the unified Parkinson's disease rating scale(UPDRS),3rd section of the UPDRS(UPDRS-Ⅲ),and motor dysfunction rating scale for Parkinson's disease(MDRSPD)were scored in the patients.The therapeutic effect of traditional Chinese medicine(TCM)and LED score were compared between both groups.Results:Thirty-three cases were included in data analysis in each group.After treatment,UPDRS scores were(28.77±8.85)and(36.58±10.16)points,UPDRS-Ⅲ scores were(12.16±1.97)and(17.47±2.93)points and MDRSPD scores were(15.56±3.31)and(19.13±4.87)points in the acupuncture+medi-cation and medication groups respectively.The UPDRS,UPDRS-Ⅲ,and MDRSPD scores all reduced after treatments in both groups(all P＜0.05).All three scores were lower in the acupuncture+medica-tion group than in the medication group(all P＜0.05).When examining the therapeutic effects of TCM,the total effective rate was 87.88％in the acupuncture+medication group and 75.76％in the medica-tion group(P＜0.05).After treatment,the LED scores were(387.55±146.24)points and(437.42±183.16)points in the acupuncture+medication and medication groups,respectively.The LED dose dif-ferences before and after treatment for the acupuncture+medication and medication groups were(40.36±16.33)points and(95.88±35.79)points,respectively.The LED scores in both groups were higher than the pre-treatment scores(P＜0.05).However,the post-treatment LED score was lower in the acupunc-ture+medication group than in the medication group(P＜0.05),as was the dose difference before and after treatment(P＜0.05).No relevant adverse reaction was found in each group.Conclusion:In addition to anti-PD medication,the scalp and body acupuncture may effectively relieve the motor symptoms of PD and improve the control of LED score.

贾元斌;王小军;刘兴平;王鹏;邓超;李中正;赵晔

泰国格乐大学国际学院公共卫生系,曼谷10200,泰国;吉首大学医学院,湖南吉首416000,中国;吉首大学附属中医院,湖南吉首416000,中国;吉首大学附属宁乡中医院,湖南长沙410600,中国;山东中医药大学细胞行为组学研究中心,济南250355,中国

世界针灸杂志（英文版）

[1]贾元斌;王小军;刘兴平;王鹏;邓超;李中正;赵晔-.头针联合体针对帕金森病运动症状的治疗效应:随机临床研究)[J].世界针灸杂志（英文版）,2022(04):342-350

acupuncture+medication,assessors,MS14,ihu,GV20,HN1,GV14,ngch,GB20,igu,nsh,BL18,ngl,ngqu,GB34,nji,ix,KI3,MDRSPD,acupuncture+medi,acupuncture+medica,acupunc,ture+medication

头针,联合体,体针,帕金森病运动症状,Objective,To,observe,therapeutic,combined,scalp,body,motor,Parkinson,disease,levodopa,equivalent,dose,LED,Methods,This,randomized,single,trial,Sixty,six,patients,were,into,aware,allocation,blinded,assignment,regimen,Anti,drugs,administered,both,groups,In,therapy,was,added,Treatments,applied,weeks,ante,rior,oblique,line,vertex,temporal,MS6,MS8,MS9,lower,occiput,selected,acupoints,included,百会,四神聪,EX,zhu,大椎,well,bilateral,风池,内关,PC6,合谷,LI4,Sh,肾俞,BL23,阳陵,nl,足三里,ST36,丰隆,ST40,ny,阴交,SP6,太溪,ich,太冲,LR3,Before,after,treatments,unified,rating,scale,UPDRS,3rd,section,dysfunction,scored,traditional,Chinese,medicine,TCM,compared,between,Results,Thirty,three,cases,data,analysis,each,After,scores,respectively,reduced,All,than,When,examining,effects,total,rate,ferences,before,higher,pre,However,post,difference,No,relevant,adverse,reaction,found,Conclusion,addition,anti,may,effectively,relieve,symptoms,improve,control

0.371004