Objective:To observe the clinical efficacy of acupuncture on dystonia in brain-type Wilson's disease(WD)with internal retention of damp heat pattern.Methods:A total of 60 patients with WD dystonia with internal retention of damp heat pattern were randomized into acupuncture and medication groups using a random number table,with 30 participants in each group.All patients had a low-copper diet and consumed dimercaptopropanesulfonate sodium(DMPS)for copper excretion.In the acupuncture group,on the base of the same treatment as that given to the medication group,acupuncture was applied at Bǎihuì(百会GV20),Shéntíng(神庭GV24),Chéngjiāng(承浆CV4),Jiānyú(肩髃LI5),Nàoshū(臑俞SI10),Wàiguān(外关TE5),Nèiguān(内关PC6),Shǒusānlǐ(手三里LI10),Hégǔ(合谷LI4),Yángxī(阳溪LI5),Huántiào(环跳GB30),Bìguān(髀关ST31),Yánglíngquán(阳陵泉GB34),Fēnglong(丰隆ST40),Zúsānlǐ(足三里ST36),Sānyīnjiāo(三阴交SP6),Xuánzhong(悬钟GB39),and Xíngjiān(行间LR2).Before and 24 days after treatment,the modified Ashworth scale(MAS)and Burke-Fahn-Marsden dystonia rating scale(BFMDRS)were used to evaluate dystonia symptoms.The allocation scheme was concealed for the outcome assessors.Results:The data of 30 cases were analyzed in each group.Before treatment,the MAS score difference between the acupuncture and medication groups was not statistically significant(P＞0.05).Compared with the score before treatment,the MAS score was lower significantly in both the acupuncture group(2.63±0.76 vs 4.50±0.78)and medication group(3.30±0.65 vs 4.40±0.77)after treatment(both P＜0.05).After treatment,the MAS score in the acupuncture group was significantly lower than that in the medication group(P＜0.01).Before treatment,the BFMDRS score was not significantly different between the two groups(P＞0.05).Compared with the score before treatment,the BFMDRS score was significantly lower in both the acupuncture(64.97±14.26 vs 85.23±16.99)and medication groups(11.33±2.60 vs 75.40±16.25)after treatment(both P＜0.05).The BFMDRS score of the acupuncture group was lower than that of the medication group after treatment(P＜0.05).During treatment,1 case had allergic reaction of DMPS in the acupuncture group,manifested as reddish skin and skin rashes,and the allergic symptoms disappeared after anti-allergic treatment.There was no any adverse reaction in the medication group.Conclusion:Combined treatment with acupuncture and Western medication is significantly effective against dystonia in brain-type WD with internal retention of damp heat pattern.

王萍;陈怀珍;李落意;杨骏;杨文明;王频

安徽中医药大学第一附属医院,合肥23003,中国;安徽中医药大学,合肥230031,中国

世界针灸杂志（英文版）

[1]王萍;陈怀珍;李落意;杨骏;杨文明;王频-.针刺治疗湿热内蕴型肝豆状核变性脑型肌张力障碍——随机临床试验)[J].世界针灸杂志（英文版）,2022(03):193-198

dimercaptopropanesulfonate,ihu,GV20,GV24,ngji,LI5,osh,SI10,igu,TE5,LI10,ngx,nti,ST31,ngl,ngqu,GB34,nglong,nji,nzhong,GB39,assessors,reddish

针刺治疗,湿热内蕴型,肝豆状核变性,脑型,肌张力障碍,随机临床试验,Objective,To,observe,clinical,efficacy,acupuncture,dystonia,brain,type,Wilson,disease,WD,internal,retention,damp,heat,pattern,Methods,total,patients,were,randomized,into,medication,groups,using,number,table,participants,each,All,had,copper,diet,consumed,sodium,DMPS,excretion,In,base,same,treatment,that,given,was,applied,百会,Sh,神庭,Ch,承浆,CV4,Ji,肩髃,内关,PC6,nl,手三里,合谷,LI4,Hu,环跳,GB30,髀关,阳陵泉,丰隆,ST40,足三里,ST36,三阴交,SP6,Xu,悬钟,行间,LR2,Before,days,after,modified,Ashworth,scale,MAS,Burke,Fahn,Marsden,rating,BFMDRS,used,evaluate,symptoms,allocation,scheme,concealed,outcome,Results,data,cases,analyzed,score,difference,between,not,statistically,Compared,before,lower,significantly,both,After,than,different,two,During,allergic,reaction,manifested,skin,rashes,disappeared,anti,There,any,adverse,Conclusion,Combined,effective,against

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