典型文献
Tabernaesine J,a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Scaffold from Tabernaemontana pachysiphon
文献摘要：
Tabernaesine J(1),an unprecedented vincamine-type indole alkaloid with 6/5/6/6/6/5/5 heptacyclic-ring system,as well as one new biogenetically related vincamine-type indole alkaloid(2),were isolated from leaves of Tabernaemontana pachysiphon.Their structures were established by a combination of HRESIMS,NMR,single crystal X-ray diffraction,and ECD calculation.The unprecedented pen-ta-lactone ring in tabernaesine J(1)was postulated to be derived from acetyl-CoA enolate anion.Alkaloid 2 combined with fluconazole has the potential to overcome fluconazole resistance in Candida albicans.
文献关键词：
中图分类号：
作者姓名：
Wen-Fang Yi;Tiwalade A.Adelakun;Xue Bai;Yu Zhang;Xiao-Jiang Hao
作者机构：
State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming,Yunnan 650201,China
文献出处：
引用格式：
[1]Wen-Fang Yi;Tiwalade A.Adelakun;Xue Bai;Yu Zhang;Xiao-Jiang Hao-.Tabernaesine J,a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Scaffold from Tabernaemontana pachysiphon)[J].中国化学（英文版）,2022(04):475-479
A类：
Tabernaesine,Vincamine,Heptacyclic,Tabernaemontana,pachysiphon,vincamine,heptacyclic,biogenetically,tabernaesine,enolate
B类：
Novel,Type,Indole,Alkaloid,Ring,System,Scaffold,from,unprecedented,type,indole,alkaloid,ring,system,well,new,related,were,isolated,leaves,Their,structures,established,by,combination,HRESIMS,NMR,single,crystal,ray,diffraction,ECD,calculation,pen,lactone,was,postulated,derived,acetyl,CoA,anion,combined,fluconazole,has,potential,overcome,resistance,Candida,albicans
AB值：
0.50657
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
