The loosening of implant due to bacterial infection brings great difficulties to the implantation of bionic titanium devices.In this study,the Zeolitic Imidazolate Framework 8(ZIF-8)and silver ions were added to the surface of titanium alloy to obtain a uniform coating,which has nice biological activity and antibacterial property.The material structure characteri-zations,such as X-ray diffraction(XRD),scanning electron microscope(SEM),X-ray photoelectron spectroscopy(XPS),proved that titanium is successfully modified with ZIF-8 and silver ions.It has micro-and nano-level characteristics,rough porous morphology,and excellent apatite inducing ability.The water contact angle experiment shows that the addition of ZIF-8 greatly increases the hydrophilicity of material,which provides conditions for the attachment of osteoblasts.The polarization curve obtained from the electrochemical test proves that the addition of ZIF-8 coating improves the corrosion resistance of titanium.The release of silver ion has a strong growth inhibitory effect on E.coli,and exhibits excellent anti-bacterial properties.Therefore,the preparation of ZIF-8/Ag coatings on 3D printed titanium provides a new option for the development of orthopedic implants.

Mingrui Li;Yongjie Wei;Bowen Ma;Yang Hu;Dongdong Li;Xiaoqiang Cui

Key Laboratory of Automobile Materials of MOE,Department of Materials Science and Engineering,Jilin University,Changchun 130022,China;State Key Laboratory for Materials Processing and Die and Mould Technology,School of Materials Science and Engineering,Huazhong University of Science and Technology,Wuhan 430074,China

仿生工程学报（英文版）

[1]Mingrui Li;Yongjie Wei;Bowen Ma;Yang Hu;Dongdong Li;Xiaoqiang Cui-.Synthesis and Antibacterial Properties of ZIF-8/Ag-Modified Titanium Alloy)[J].仿生工程学报（英文版）,2022(02):507-515

Imidazolate,zations

Synthesis,Antibacterial,Properties,ZIF,Ag,Modified,Titanium,Alloy,loosening,due,infection,brings,difficulties,implantation,bionic,titanium,devices,In,this,study,Zeolitic,Framework,silver,were,added,surface,alloy,uniform,which,has,nice,biological,activity,antibacterial,property,material,structure,such,ray,diffraction,scanning,microscope,photoelectron,spectroscopy,XPS,proved,that,successfully,modified,It,nano,level,characteristics,rough,porous,morphology,excellent,apatite,inducing,ability,water,contact,angle,experiment,shows,addition,greatly,increases,hydrophilicity,provides,conditions,attachment,osteoblasts,polarization,curve,obtained,from,electrochemical,test,improves,corrosion,resistance,release,strong,growth,inhibitory,effect,coli,exhibits,properties,Therefore,preparation,coatings,printed,new,option,development,orthopedic,implants

0.615699