Background:Abdominal pain is often observed after endoscopic retrograde cholangiopancreatography(ERCP).Few studies have focused on the risk factors of post-ERCP abdominal pain without post-ERCP pancreatitis(PEP).This study aimed to identify risk factors of post-ERCP abdominal pain without PEP and investigate characteristics of the abdominal pain in non-PEP patients.Methods:Data from patients who underwent ERCP from August 2019 to January 2020 were retrospec-tively collected.Characteristics of the abdominal pain after ERCP were recorded and compared between PEP and non-PEP patients.Multivariate analysis was conducted to identify risk factors of non-PEP abdom-inal pain.Results:A total of 1295 ERCP procedures were investigated in this study,among which 100(7.72％)pa-tients presented post-ERCP abdominal pain without PEP and 63(4.86％)patients with PEP.Multivariate analysis found 9 risk factors of non-PEP abdominal pain:age≤65 years[odds ratio(OR):1.971],primary ERCP(OR:2.442),dilated extrahepatic bile duct(OR:1.803),no papilla opening(OR:2.095),pancreatic guidewire passages(OR:2.258),white blood cells(WBC)≤6.0×109/L(OR:1.689),platelet(PLT)≤250×109/L(OR:2.505),serum γ-glutamyl transferase(γ-GT)≤35 U/L(OR:2.190),and albumin≥40 g/L(OR:1.762).The PEP group had later pain onset,higher pain frequency and longer hospital stay than those of the non-PEP pain group(P＜0.05).There were no significant differences in the pain duration,visual analogue scale score and mortality between the PEP group and non-PEP pain group(P＞0.05).Conclusions:This study indicated that age≤65 years,primary ERCP,dilated extrahepatic bile duct,no papilla opening,pancreatic guidewire passages,lower WBC,lower PLT,normal γ-GT and elevated albu-min were independent risk factors for post-ERCP abdominal pain without PEP.The pain occurred earlier in non-PEP patients than in PEP patients.

Meng-Jie Chen;Ru-Hua Zheng;Jun Cao;Yu-Ling Yao;Lei Wang;Xiao-Ping Zou

Department of Gastroenterology,Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University,Nanjing,China;Department of Gastroenterology,Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjing,China

国际肝胆胰疾病杂志(英文版)

[1]Meng-Jie Chen;Ru-Hua Zheng;Jun Cao;Yu-Ling Yao;Lei Wang;Xiao-Ping Zou-.Risk factors for post-endoscopic retrograde cholangiopancreatography(ERCP)abdominal pain in patients without post-ERCP pancreatitis)[J].国际肝胆胰疾病杂志(英文版),2022(03):285-292

retrospec,abdom,guidewire

Risk,factors,post,endoscopic,retrograde,cholangiopancreatography,ERCP,abdominal,pain,patients,without,pancreatitis,Background,Abdominal,often,observed,after,Few,studies,have,focused,risk,PEP,This,study,aimed,identify,characteristics,Methods,Data,from,who,underwent,August,January,were,tively,collected,Characteristics,recorded,compared,between,Multivariate,analysis,was,conducted,Results,total,procedures,investigated,this,among,which,presented,found,years,odds,primary,dilated,extrahepatic,bile,papilla,opening,pancreatic,passages,white,blood,cells,WBC,platelet,PLT,serum,glutamyl,transferase,GT,albumin,group,had,later,onset,higher,frequency,longer,hospital,stay,than,those,There,significant,differences,duration,visual,analogue,scale,score,mortality,Conclusions,indicated,that,lower,normal,elevated,independent,occurred,earlier

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