典型文献
Schistosoma japonicum Eggs Exerts Protective Effects in an Experimental Ulcerative Colitis Model
文献摘要：
Ulcerative colitis (UC) is a chronic inflammatory disease affecting the colon, with an increasing incidence worldwide. Disease pathogenesis is multifactorial and involves genetic predisposition, epithelial barrier defects, dysregulated immune responses, and environmental factors[1,2]. Long-standing UC leads to several complications such as megacolon, inflammation of the eye and joints, and/or colon cancer[3]. Eaden et al. revealed that 25-year chronic UC increases colorectal cancer risk by as much as 34％[4]. Their study further indicated that UC etiology is related to the environment, gene variation, intestinal microflora, and altered immune response, but precise mechanisms and pathogenesis remain unclear. Several drugs and surgical approaches are used to treat UC, but may present drug resistance issues or severe side effects[5]. Therefore, novel UC treatments are demanded.
文献关键词：
中图分类号：
作者姓名：
MA Zhen Rong;SUN Xi;ZHENG Wen Xiao;LI Xuan Wu;ZHANG Ni;HUANG Ye Hong;LU Bin;LI Zhuo Lin;NOUHOUM Di Bo;YU Xin Ling;ZHOU Jie;CHEN Hong Zhi;YANG Xue Xian;WU Xiang
作者机构：
Department of Parasitology,School of Basic Medical Sciences,Xiangya School of Medicine,Central South University,Changsha 410000,Hunan,China;Department of Urology,Second Affiliated Hospital of Sun Yat-sen University,Guangzhou 510120,Guangdong,China;Clinical Medicine,Xiangya School of Medicine,Central South University,Changsha 410000,Hunan,China;Hunan Institute of Parasite Disease,WHO Collaborating Center For Research and Control on Schistosomiasis in Lake Region,Yueyang 414000,Hunan,China;National Clinical Research Center for Metabolic Disease,Key Laboratory of Diabetes Immunology,Ministry of Education,and Department of Metabolism and Endocrinology,The Second Xiangya Hospital,Central South University,Changsha 410000,Hunan,China;Department of Molecular&Genetic and Microbiology,University of New Mexico School of Medicine,Albuquerque,NM 87131,USA
文献出处：
引用格式：
[1]MA Zhen Rong;SUN Xi;ZHENG Wen Xiao;LI Xuan Wu;ZHANG Ni;HUANG Ye Hong;LU Bin;LI Zhuo Lin;NOUHOUM Di Bo;YU Xin Ling;ZHOU Jie;CHEN Hong Zhi;YANG Xue Xian;WU Xiang-.Schistosoma japonicum Eggs Exerts Protective Effects in an Experimental Ulcerative Colitis Model)[J].生物医学与环境科学（英文版）,2022(11):1085-1089
A类：
Exerts,megacolon,Eaden
B类：
Schistosoma,japonicum,Eggs,Protective,Effects,Experimental,Ulcerative,Colitis,Model,colitis,UC,chronic,inflammatory,disease,affecting,increasing,incidence,worldwide,Disease,pathogenesis,multifactorial,involves,genetic,predisposition,epithelial,barrier,defects,dysregulated,immune,responses,environmental,factors,Long,standing,leads,several,complications,such,inflammation,eye,joints,cancer,revealed,that,year,increases,colorectal,risk,by,much,Their,study,further,indicated,etiology,related,variation,intestinal,microflora,altered,but,precise,mechanisms,remain,unclear,Several,drugs,surgical,approaches,are,used,may,present,resistance,issues,severe,side,effects,Therefore,novel,treatments,demanded
AB值：
0.672547
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
