典型文献
Effects of targeted muscle reinnervation on spinal cord motor neurons in rats following tibial nerve transection
文献摘要：
Targeted muscle reinnervation (TMR) is a surgical procedure used to transfer residual peripheral nerves from amputated limbs to targeted muscles, which allows the target muscles to become sources of motor control information for function reconstruction. However, the effect of TMR on injured motor neurons is still unclear. In this study, we aimed to explore the effect of hind limb TMR surgery on injured motor neurons in the spinal cord of rats after tibial nerve transection. We found that the reduction in hind limb motor function and atrophy in mice caused by tibial nerve transection improved after TMR. TMR enhanced nerve regeneration by increasing the number of axons and myelin sheath thickness in the tibial nerve, increasing the number of anterior horn motor neurons, and increasing the number of choline acetyltransferase-positive cells and immunofluorescence intensity of synaptophysin in rat spinal cord. Our findings suggest that TMR may enable the reconnection of residual nerve fibers to target muscles, thus restoring hind limb motor function on the injured side.
文献关键词：
中图分类号：
作者姓名：
Wei Lu;Jian-Ping Li;Zhen-Dong Jiang;Lin Yang;Xue-Zheng Liu
作者机构：
Department of Human Anatomy,School of Basic Medical Scinences,Guangxi Medical University,Nanning,Guangxi Zhuang Autonomous Region,China;Department of Human Anatomy,Zhuhai Campus of Zunyi Medical University,Zhuhai,Guangdong Province,China
文献出处：
引用格式：
[1]Wei Lu;Jian-Ping Li;Zhen-Dong Jiang;Lin Yang;Xue-Zheng Liu-.Effects of targeted muscle reinnervation on spinal cord motor neurons in rats following tibial nerve transection)[J].中国神经再生研究（英文版）,2022(08):1827-1832
A类：
reinnervation
B类：
Effects,targeted,spinal,cord,motor,neurons,rats,following,tibial,transection,Targeted,TMR,surgical,procedure,residual,peripheral,nerves,from,amputated,limbs,muscles,which,allows,become,sources,control,information,function,reconstruction,However,effect,injured,still,unclear,In,this,study,aimed,explore,hind,surgery,after,We,found,that,reduction,atrophy,mice,caused,by,improved,enhanced,regeneration,increasing,number,axons,myelin,sheath,thickness,anterior,horn,choline,acetyltransferase,positive,cells,immunofluorescence,intensity,synaptophysin,Our,findings,suggest,may,enable,reconnection,fibers,thus,restoring,side
AB值：
0.48259
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
