典型文献
Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis
文献摘要：
INTRODUCTION
BRONJ is one of the medication-related osteonecrosis of the jaw (MRONJ).1–2 Patients have a history of using bisphosphonates to treat osteoporosis, tumor bone metastasis, and other diseases. Patients can have persistent pain, pus, limited mouth opening, long-lasting skin fistula and, even pathological fractures, which seriously affect the patients' life, but there is still short of effective prevention and treatment measures in the medical community.3–4 At present, scholars have put forward a variety of hypotheses about the pathogenesis of BRONJ, mainly including inhibition of bone remodeling, reduction of angiogenesis, direct tissue toxicity, oral microbial infection, immunosuppression and so on, but its exact pathogenesis is still unclear.
文献关键词：
中图分类号：
作者姓名：
Dan Zhao;Dexuan Xiao;Mengting Liu;Jiajie Li;Shuanglin Peng;Qing He;Yue Sun;Jingang Xiao;Yunfeng Lin
作者机构：
State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of Oral and Maxillofacial Surgery,West China Hospital of Stomatology,Sichuan University,Chengdu,China;Department of Oral and Maxillofacial Surgery,The Affiliated Stomatology Hospital of Southwest Medical University,Luzhou,China
文献出处：
引用格式：
[1]Dan Zhao;Dexuan Xiao;Mengting Liu;Jiajie Li;Shuanglin Peng;Qing He;Yue Sun;Jingang Xiao;Yunfeng Lin-.Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis)[J].国际口腔科学杂志（英文版）,2022(02):201-211
A类：
BRONJ,bisphosphonates
B类：
Tetrahedral,framework,nucleic,acid,carrying,angiogenic,peptide,prevents,related,osteonecrosis,jaw,by,promoting,angiogenesis,INTRODUCTION,medication,MRONJ,Patients,have,history,using,osteoporosis,tumor,bone,metastasis,other,diseases,can,persistent,pain,pus,limited,mouth,opening,long,lasting,skin,fistula,pathological,fractures,which,seriously,affect,patients,life,but,there,still,short,effective,prevention,treatment,measures,medical,community,At,present,scholars,put,forward,variety,hypotheses,about,pathogenesis,mainly,including,inhibition,remodeling,reduction,direct,tissue,toxicity,oral,microbial,infection,immunosuppression,so,its,exact,unclear
AB值：
0.716634
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
