典型文献
Biomolecule@COF:Natural-artificial hybrid microcapsules for controllable biocatalysis
文献摘要：
The assembly of biomacromole particles with artificial solid matrixes to fabricate hybrid composites has been demonstrated as an efficient strategy to promote both components' applications.Elaborating matrixes as well as appropriate assembly method is essential for optimal performances of the obtained natural-artificial composites.Herein,we fabricated the Cyt c@COF-42-B microcapsule through a sacrificial templating method and researched their adjustable biocatalysis by precisely adjusting the microenviron-ments of these assembled enzyme@COF particles.As a result,the hydrophobicity and mass transfer of the COF microcapsule can be controlled by modifying the different amounts of PEG moieties,thus improving the composite's bioactivity.We found that compared with pristine Cyt c@COF-42-B without PEG,the Cyt c@COF-42-B-PEG exhibited a ～2.2 times higher activity.This study provides a significant step toward designing customizable functional natural-artificial composites for enhanced biomacromolecule's activ-ity.
文献关键词：
中图分类号：
作者姓名：
Shan Qiao;Mingmin Li;Jiangyue Yu;Sainan Zhang;Dong Yan;Zhenjie Zhang;Yao Chen
作者机构：
State Key Laboratory of Medicinal Chemical Biology,College of Pharmacy,Nankai University,Tianjin 300071,China;Life and Health Research Institute,School of Chemistry and Chemical Engineering Tianjin University of Technology,Tianjin 300384,China;College of Chemistry,Nankai University,Tianjin 300071,China
文献出处：
引用格式：
[1]Shan Qiao;Mingmin Li;Jiangyue Yu;Sainan Zhang;Dong Yan;Zhenjie Zhang;Yao Chen-.Biomolecule@COF:Natural-artificial hybrid microcapsules for controllable biocatalysis)[J].颗粒学报（英文版）,2022(05):140-144
A类：
Biomolecule,biomacromole
B类：
COF,Natural,artificial,hybrid,microcapsules,controllable,biocatalysis,assembly,particles,solid,matrixes,composites,has,been,demonstrated,efficient,strategy,promote,both,components,applications,Elaborating,well,appropriate,method,essential,optimal,performances,obtained,natural,Herein,fabricated,Cyt,through,sacrificial,templating,researched,their,adjustable,by,precisely,adjusting,microenviron,ments,these,assembled,enzyme,result,hydrophobicity,mass,transfer,controlled,modifying,different,amounts,PEG,moieties,thus,improving,bioactivity,We,found,that,compared,pristine,without,exhibited,times,higher,This,study,provides,significant,step,toward,designing,customizable,functional,enhanced,biomacromolecule
AB值：
0.605994
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