典型文献
Structural basis for the gating modulation of Kv4.3 by auxiliary subunits
文献摘要：
Dear Editor,
Kv4.3 is an A-type voltage-gated potassium channel that is characterized by fast activation at subthreshold membrane potentials,rapid inactivation,and quick recovery from inactiva-tion.1 In neurons,Kv4.3 conducts the transient subthreshold somatodendritic A-type potassium current(ISA),knock down of which results in neuropathic pain and epilepsy.2 In cardiomyo-cytes,Kv4.3 generates the transient outward potassium current(lto)and its dysfunction is related to a variety of heart diseases,such as hypertrophy,heart failure,myocardial infarction,heart valvular disease,atrial fibrillation,and diabetic cardiomyopathy.
文献关键词：
中图分类号：
作者姓名：
Demin Ma;Cheng Zhao;Xiaochen Wang;Xiaoxiao Li;Yi Zha;Yan Zhang;Guosheng Fu;Ping Liang;Jiangtao Guo;Dongwu Lai
作者机构：
Department of Biophysics,and Department of Pathology of Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang,China;Department of Cardiology,Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang,China;Key Laboratory of Combined Multi-organ Transplantation,Ministry of Public Health,the First Affiliated Hospital,and Institute of Translational Medicine,Zhejiang University School of Medicine,Hangzhou,Zhejiang,China;State Key Laboratory of Plant Physiology and Biochemistry,College of Life Sciences,Zhejiang University,Hangzhou,Zhejiang,China;Cancer Center,Zhejiang University,Hangzhou,Zhejiang,China;Liangzhu Laboratory,Zhejiang University Medical Center,Hangzhou,Zhejiang,China
文献出处：
引用格式：
[1]Demin Ma;Cheng Zhao;Xiaochen Wang;Xiaoxiao Li;Yi Zha;Yan Zhang;Guosheng Fu;Ping Liang;Jiangtao Guo;Dongwu Lai-.Structural basis for the gating modulation of Kv4.3 by auxiliary subunits)[J].细胞研究（英文版）,2022(04):411-414
A类：
Kv4,somatodendritic,cardiomyo,lto
B类：
Structural,basis,gating,modulation,by,auxiliary,subunits,Dear,Editor,type,voltage,gated,potassium,channel,that,characterized,fast,subthreshold,membrane,potentials,rapid,inactivation,quick,recovery,from,In,neurons,conducts,transient,current,ISA,knock,down,which,results,neuropathic,pain,epilepsy,cytes,generates,outward,dysfunction,related,variety,heart,diseases,such,hypertrophy,failure,myocardial,infarction,valvular,atrial,fibrillation,diabetic,cardiomyopathy
AB值：
0.615205
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
