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典型文献
Revealing the secret behind Smo cholesterylation
文献摘要:
The GPCR family protein Smoothened(Smo)transduces Hedgehog signal across the plasma membrane.In a recent paper published in Cell Research,Hu et al.discovered that Smoothened undergoes an auto-cholesterylation process facilitated by calcium and demonstrated that covalent cholesterol attachment to Smo cysteine-rich domain is required for Hedgehog signal transduction.
文献关键词:
作者姓名:
Yuhong Han;Jin Jiang
作者机构:
Department of Molecular Biology,UT Southwestern Medical Center,Dallas,TX,USA;Department of Pharmacology,UT Southwestern Medical Center,Dallas,TX,USA
引用格式:
[1]Yuhong Han;Jin Jiang-.Revealing the secret behind Smo cholesterylation)[J].细胞研究(英文版),2022(04):327-328
A类:
cholesterylation
B类:
Revealing,secret,behind,GPCR,family,protein,Smoothened,transduces,Hedgehog,signal,across,plasma,membrane,In,recent,paper,published,Cell,Research,Hu,discovered,that,undergoes,auto,process,facilitated,by,calcium,demonstrated,covalent,cholesterol,attachment,cysteine,rich,domain,required,transduction
AB值:
0.656427
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