典型文献
Cadherin 11-mediated juxtacrine interaction of gastric cancer cells and fibroblasts promotes metastasis via YAP/tenascin-C signaling
文献摘要：
Gastric cancer(GC)is the fifth most common cancer and the third leading cause of cancer-related death worldwide[1].Metas-tasis is the leading cause of GC mortality.The complex dynamic interactions between tumor cells and stromal cells in the tumor microenvironment are crucial for tumor metastasis.Many secreted cytokines have been well documented to mediate the crosstalk between tumor cells and stromal cells in a paracrine manner[2].However,how the juxtacrine signals transduced by adjacent cell-cell adhesion modulate cancer metastasis has yet to be elucidated[3].As one of the most important cell-cell adhesion molecules,the classical cadherin superfamily also initiates different intracellular signaling cascades and regulates cytoskeletal dynamics,perme-ability,cell polarity,and tumor progression[4,5].
文献关键词：
中图分类号：
作者姓名：
Jiaojiao Ni;Mingchun Jiang;Yanyan Chen;Xianping Rao;Junjie Jiang;Zizhen Zhang;Fangyu Ju;Dongyang Guo;Boya Wang;Lisong Teng;Liangjing Wang;Tianhua Zhou;Wei Zhuo
作者机构：
Department of Cell Biology and Department of Gastroenterology,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310016,China;Department of Gastroenterology,The Second Affiliated Hospital Zhejiang University School of Medicine,Hangzhou 310002,China;Cancer Center,Zhejiang University,Hangzhou 310058,China;Institute of Gastroenterology,Zhejiang University,Hangzhou 310002,China;Department of Surgical Oncology,The First Affiliated Hospital Zhejiang University School of Medicine,Hangzhou 310002,China;Department of Molecular Genetics,University of Toronto,Toronto ON M5S 1A8,Canada
文献出处：
引用格式：
[1]Jiaojiao Ni;Mingchun Jiang;Yanyan Chen;Xianping Rao;Junjie Jiang;Zizhen Zhang;Fangyu Ju;Dongyang Guo;Boya Wang;Lisong Teng;Liangjing Wang;Tianhua Zhou;Wei Zhuo-.Cadherin 11-mediated juxtacrine interaction of gastric cancer cells and fibroblasts promotes metastasis via YAP/tenascin-C signaling)[J].科学通报（英文版）,2022(10):1026-1030
A类：
juxtacrine
B类：
Cadherin,mediated,gastric,cancer,cells,fibroblasts,promotes,metastasis,via,YAP,tenascin,signaling,Gastric,fifth,most,common,third,leading,cause,related,death,worldwide,Metas,mortality,complex,interactions,between,tumor,stromal,microenvironment,are,crucial,Many,secreted,cytokines,have,been,well,documented,crosstalk,paracrine,manner,However,how,signals,transduced,by,adjacent,adhesion,modulate,has,yet,elucidated,one,important,molecules,classical,cadherin,superfamily,also,initiates,different,intracellular,cascades,regulates,cytoskeletal,dynamics,perme,ability,polarity,progression
AB值：
0.635761
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
