典型文献
Palladium Nanoparticles/Graphdiyne Oxide Nanocomposite with Excellent Peroxidase-like Activity and Its Application for Glutathione Detection
文献摘要：
In this study,palladium nanoparticles loaded graphdiyne oxide(Pd/GDYO)nanocomposite were fabricated by in-situ reduction of palladium chloride in the dispersion of GDYO,and characte-rized by Raman spectra,transmission electron microscopy,X-ray dif-fraction and X-ray photoelectron spectroscopy.The synthesized Pd/GDYO was first found to have catalytic activities similar to those of the peroxidase enzyme,which can catalyze the oxidation of peroxidase substrate 3,3',5,5'-tetramethylbenzidine(TMB)in the presence of hydrogen peroxide(H202).Steady-state kinetic studies showed that the catalytic reaction of Pd/GDYO follows a ping-pong mechanism,and Pd/GDYO has a stronger activity to TMB with a Michaelis constant(Km)value of 5.32×10-4 mmol/L.Based on the shielding effect of glutathione(GSH)on the Pd/GDYO-H202-TMB reaction system,a colorimetric detection method for GSH was deve-loped with a wide linear range from 0.1 μmol/L to 40 μmol/L and a limit of detection of 0.1 μmol/L.The method was successfully applied for fast and accurate detection of GSH in injection powder drugs.It was expected that this peroxidase-like Pd/GDYO nano-composite would have wide applications in the fields of biomedicine and environmental chemistry.
文献关键词：
中图分类号：
作者姓名：
LAN Weifei;HU Ruifeng;HUANG Danrong;DONG Xu;SHEN Gangyi;CHANG Shan;DAI Dongsheng
作者机构：
School of Pharmacy,Minzu University of China,Beijing 100081,P.R.China;Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,P.R.China;Institute of Bioinformatics and Medical Engineering,School of Electrical and Information Engineering,Jiangsu University of Technology,Changzhou 213001,P.R.China
文献出处：
引用格式：
[1]LAN Weifei;HU Ruifeng;HUANG Danrong;DONG Xu;SHEN Gangyi;CHANG Shan;DAI Dongsheng-.Palladium Nanoparticles/Graphdiyne Oxide Nanocomposite with Excellent Peroxidase-like Activity and Its Application for Glutathione Detection)[J].高等学校化学研究（英文版）,2022(02):529-534
A类：
characte
B类：
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AB值：
0.645361
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