典型文献
The programmed death of fetal oocytes and the correlated surveillance mechanisms
文献摘要：
Gamete production is essential for mammalian reproduction. In the ovaries, the primordial follicle, which is the basic reproductive unit, is formed either perinatally or during the second pregnancy stage in humans. However, some oocytes die before the establishment of the primordial follicle pool. Consequently, it is essential to uncover how the size of the primordial follicle pool is determined and how the programmed cell death of oocytes is performed under potential surveillance. According to recent studies, the fate of oocytes in the fetal ovary seems to be determined by different protective strategies through the timely control of apoptosis or autophagy. In this review, we discuss at least three oocyte-derived protective biomarkers, glycogen synthase kinase 3 beta, X-linked inhibitor of apoptosis, and Lysine-specific demethylase 1 (also known as KDM1A), responsible for surveilling the developmental quality of fetal oocytes to coordinate primordial follicle formation in the fetal ovary. This review contributes to a better understanding of the secrets of the female reproductive reserve under physiological conditions.
文献关键词：
Oocyte;Primordial follicle formation;Protective mechanism;Apoptosis;Autophagy
中图分类号：
作者姓名：
Zhou Jia-Qi;Wang Wen-Ji;Xia Guo-Liang;Wang Chao
作者机构：
State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China;School of Life Sciences, Taizhou University, Taizhou, Zhejiang 318000, China;Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in Western China, College of Life Science, Ningxia University, Yinchuan 750021, China
文献出处：
引用格式：
[1]Zhou Jia-Qi;Wang Wen-Ji;Xia Guo-Liang;Wang Chao-.The programmed death of fetal oocytes and the correlated surveillance mechanisms)[J].生殖与发育医学（英文）,2022(03):181-193
A类：
Gamete,perinatally,surveilling
B类：
programmed,death,fetal,oocytes,correlated,surveillance,mechanisms,essential,mammalian,reproduction,In,ovaries,primordial,follicle,which,basic,reproductive,unit,either,during,second,pregnancy,stage,humans,However,some,before,establishment,pool,Consequently,uncover,how,size,determined,cell,performed,potential,According,recent,studies,fate,ovary,seems,by,different,protective,strategies,through,timely,control,apoptosis,autophagy,this,review,discuss,least,three,derived,biomarkers,glycogen,synthase,kinase,beta,linked,inhibitor,Lysine,specific,demethylase,also,known,KDM1A,responsible,developmental,quality,coordinate,formation,This,contributes,better,understanding,secrets,female,reserve,physiological,conditions,Oocyte,Primordial,Protective,Apoptosis,Autophagy
AB值：
0.557698
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
