典型文献
Regulation of angiogenesis by microRNAs and long non-coding RNAs in endometriosis
文献摘要：
Endometriosis (EM) is a benign gynecological disease that affects the fertility and health of women of reproductive age; it is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Although several hypotheses have been proposed to explain the underlying cause of EM, its pathogenesis remains obscure. Recently, non-coding RNAs were reported to be involved in the occurrence and development of EM. MicroRNAs and long non-coding RNAs are the main members of the non-coding RNA family that contribute to EM progression in various aspects, such as cell proliferation, apoptosis, invasion, and angiogenesis. Angiogenesis plays a pivotal role in the initiation and development of EM and provides a substantial background for the invasion, proliferation, and long-term growth of endometriotic implants. This review aimed to investigate the role of microRNAs and long non-coding RNAs in regulating angiogenesis in EM and discuss how this mechanism can be used for diagnostic and therapeutic purposes in EM.
文献关键词：
MicroRNAs;Long non-coding RNAs;Endometriosis;Angiogenesis;Pathogenesis
中图分类号：
作者姓名：
Lu Rui-Hui;Zhu Jing-Wen;Li Fang-Yuan;Xue Qing
作者机构：
Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China
文献出处：
引用格式：
[1]Lu Rui-Hui;Zhu Jing-Wen;Li Fang-Yuan;Xue Qing-.Regulation of angiogenesis by microRNAs and long non-coding RNAs in endometriosis)[J].生殖与发育医学（英文）,2022(03):133-137
A类：
endometriotic
B类：
Regulation,angiogenesis,by,microRNAs,long,coding,endometriosis,Endometriosis,EM,benign,gynecological,disease,that,affects,fertility,health,women,reproductive,age,characterized,presence,endometrial,glands,stroma,outside,uterine,cavity,Although,several,hypotheses,have,been,proposed,explain,underlying,cause,its,pathogenesis,remains,obscure,Recently,were,reported,involved,occurrence,development,MicroRNAs,are,members,family,contribute,progression,various,aspects,such,cell,proliferation,apoptosis,invasion,Angiogenesis,plays,pivotal,role,initiation,provides,substantial,background,term,growth,implants,This,review,aimed,investigate,regulating,discuss,how,this,mechanism,can,used,diagnostic,therapeutic,purposes,Long,Pathogenesis
AB值：
0.592788
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