Background:Lung cancer is one of the most common cancers globally with high incidence and mortality rate.Acupuncture and moxibustion have been used as adjuvant therapies to relieve the symptoms and complications of lung cancer.At present,acupuncture and moxibustion can partially improve the quality of life(QOL)of cancer patients.However,the evidence that acupuncture and moxibustion can improve patient-reported outcomes(PROs)in patients with lung cancer is still insufficient.We aimed to conduct a systematic review and meta-analysis of published randomized controlled trials(RCTs)to determine whether acupuncture and moxibustion can improve PROs among patients with lung cancer,providing a support basis for acupuncture and moxibustion inclusion in relevant guidelines.Methods:We will search the following electronic databases:PubMed,Embase,Cochrane Library,Web of Science,CNKI,CQVIP,Wanfang Data,Sinomed,and gray literature including the ClinicalTrials.gov Database(clinicaltrials.gov)and Chinese Clinical Trial Register(chictr.org.cn).All English and Chinese articles will be searched until July 1,2021.Two researchers independently extracted data.Any disagreement was resolved by discussion until consensus was reached or by consulting a third researcher.The primary outcomes mainly included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire(EORTC QLQ-C30),functional assessment of cancer therapy-lung(FACT-L),and Karnof-sky Performance Status(KPS).The secondary outcomes included improvement of individual lung cancer-related symptoms and the safety of acupuncture intervention.Discussion:Our study is the first to focus on the PROs of acupuncture and moxibustion for lung cancer treatment.The results will contribute to a deeper understanding of the evidence distribution of acupunc-ture and moxibustion in PROs,which may support the use of acupuncture and moxibustion in lung cancer patients.

奚紫琦;魏绪强;叶子;王珂;周嘉

上海中医药大学附属岳阳中西医结合医院针麻临床研究室,上海200437,中国

世界针灸杂志（英文版）

[1]奚紫琦;魏绪强;叶子;王珂;周嘉-.针灸治疗肺癌患者报告结局:一项系统综述和荟萃分析的研究方案)[J].世界针灸杂志（英文版）,2022(04):271-276

chictr,acupunc

针灸治疗,肺癌患者,患者报告结局,系统综述,荟萃分析,研究方案,Background,Lung,one,most,common,cancers,globally,high,incidence,mortality,rate,Acupuncture,moxibustion,have,been,used,adjuvant,therapies,relieve,symptoms,complications,lung,At,present,acupuncture,partially,quality,life,QOL,patients,However,evidence,that,reported,outcomes,PROs,still,insufficient,aimed,conduct,systematic,review,meta,analysis,published,randomized,controlled,RCTs,determine,whether,among,providing,support,basis,inclusion,relevant,guidelines,Methods,will,following,electronic,databases,Embase,Cochrane,Library,CQVIP,Wanfang,Sinomed,gray,literature,including,ClinicalTrials,gov,Database,clinicaltrials,Chinese,Register,org,cn,All,English,articles,searched,until,July,Two,researchers,independently,extracted,Any,disagreement,was,resolved,by,discussion,consensus,reached,consulting,third,primary,mainly,included,European,Organization,Research,Treatment,Cancer,Quality,Life,Questionnaire,EORTC,QLQ,C30,functional,assessment,therapy,FACT,Karnof,sky,Performance,Status,KPS,secondary,improvement,individual,related,safety,intervention,Discussion,Our,study,first,focus,treatment,results,contribute,deeper,understanding,distribution,which,may

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