首站-论文投稿智能助手
典型文献
Strategies for Inhibition and Disaggregation of Amyloid-β Fibrillation
文献摘要:
Amyloid-β protein(Aβ)is a fatal cause of Alzheimer's disease,which can trigger a series of cytotoxicity by the abnormal aggregation of Aβ in human brain.The strategies for inhibition and disaggregation of Aβ fibrillation are mostly based on the interaction between monomers,oligomers,fibrils,and materials.This review summarizes recent researches of materials and regulation of interactions for inhibiting Aβ aggregation and disaggregating Aβ fibrils.The materials have been reviewed and divided into several kinds according to molecular type.And the regulation of interactions between materials and Aβ protein mainly focuses on covalent interaction,non-covalent interaction and photoactivated effect based on covalent and non-covalent interaction.In this review,the photodynamic effect and photothermal effect on regulation of Aβ aggregation are summarized in detail.In the end,the challenges and outlook of the application prospects on the strategies for inhibition and disaggregation of Aβ fibrillation are estimated.
文献关键词:
作者姓名:
Hao Geng;Dong Gao;Zijuan Wang;Xiaoning Liu;Zhanshuo Cao;Chengfen Xing
作者机构:
School of Materials Science and Engineering,Hebei University of Technology,Tianjin 300130,China;Key Laboratory of Hebei Province for Molecular,Biophysics Institute of Biophysics,School of Science,Hebei University of Technology,Tianjin 300130,China;College of Chemical Engineering,Hebei University of Technology,Tianjin 300130,China
引用格式:
[1]Hao Geng;Dong Gao;Zijuan Wang;Xiaoning Liu;Zhanshuo Cao;Chengfen Xing-.Strategies for Inhibition and Disaggregation of Amyloid-β Fibrillation)[J].中国化学(英文版),2022(04):524-538
A类:
disaggregating,photoactivated
B类:
Strategies,Inhibition,Disaggregation,Amyloid,Fibrillation,protein,fatal,cause,Alzheimer,disease,which,can,trigger,series,cytotoxicity,by,abnormal,human,brain,strategies,inhibition,disaggregation,fibrillation,are,mostly,between,monomers,oligomers,fibrils,materials,This,summarizes,recent,researches,regulation,interactions,inhibiting,have,been,reviewed,divided,into,several,kinds,according,molecular,type,And,mainly,focuses,covalent,effect,this,photodynamic,photothermal,summarized,detail,end,challenges,outlook,application,prospects,estimated
AB值:
0.530669
相似文献
Recent Advancements on Photothermal Conversion and Antibacterial Applications over MXenes-Based Materials
Shuyan Hao;Hecheng Han;Zhengyi Yang;Mengting Chen;Yanyan Jiang;Guixia Lu;Lun Dong;Hongling Wen;Hui Li;Jiurong Liu;Lili Wu;Zhou Wang;Fenglong Wang-Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of Education,Shandong University,Jinan 250061,People's Republic of China;Department of Virology,School of Public Health,Shandong University,Jinan 250012,People's Republic of China;Shenzhen Research Institute of Shandong University,A301 Virtual University Park in South District of Nanshan High-Tech Zone,Shenzhen 518057,People's Republic of China;School of Civil Engineering,Qingdao University of Technology,Qingdao 266033,People's Republic of China;Department of Breast Surgery,Qilu Hospital,Shandong University,Jinan 250012,People's Republic of China
Boron-doped Covalent Triazine Framework for Efficient CO2 Electroreduction
YI Jundong;LI Qiuxia;CHI Shaoyi;HUANG Yuanbiao;CAO Rong-Institute of New Materials & Industry Technology,Wenzhou University,Wenzhou 325027,P.R.China;School of Chemistry and Materials Science,Collaborative Innovation Center of Chemistry for Energy Materials(iChEM),University of Science and Technology of China,Hefei 230026,P.R.China;College of Chemistry,Fuzhou University,Fuzhou 350108,P.R.China;State Key Laboratory of Structural Chemistry,Fujian Institute of Research on the Structure of Matter,Chinese Academy of Sciences,Fuzhou 350025,P.R.China;University of the Chinese Academy of Sciences,Beijing 100049,P.R.China;Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China,Fuzhou 350108,P.R.China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。