典型文献
Polydeoxyribonucleotide:A promising skin anti-aging agent
文献摘要：
Polydeoxyribonucleotide(PDRN)consists of DNA fragments with molecular weights ranging from 50 to 1 500 kDa,which are mainly extracted from the sperm cells of salmon trout or chum salmon.Many preclinical and clinical studies have demonstrated the properties of PDRN.These include anti-inflammatory,anti-apoptotic,anti-osteoporotic,anti-melanogenetic,anti-allodynic,anti-osteonecrotic,bone regenerative,tissue damage preventive,anti-ulcerative,and wound healing properties,which are mediated by the activation of the adenosine A2A receptor and salvage pathways.Moreover,PDRN promotes angiogenesis,cellular activity,collagen synthesis,soft tissue regeneration,and skin priming and revitalization and can be used to treat hyperpigmentation.Therefore,this review assessed the potential use of PDRN as an anti-aging agent for the skin.
文献关键词：
中图分类号：
作者姓名：
Aawrish Khan;Guobao Wang;Feng Zhou;Lunli Gong;Jun Zhang;Lili Qi;Haiyan Cui
作者机构：
Department of Plastic and Cosmetic Surgery,Tongji Hospital of Tongji University,Shanghai,200065,China
文献出处：
引用格式：
[1]Aawrish Khan;Guobao Wang;Feng Zhou;Lunli Gong;Jun Zhang;Lili Qi;Haiyan Cui-.Polydeoxyribonucleotide:A promising skin anti-aging agent)[J].中国整形与重建外科（英文）,2022(04):187-193
A类：
Polydeoxyribonucleotide,PDRN,chum,melanogenetic,allodynic,osteonecrotic
B类：
promising,skin,anti,aging,agent,consists,fragments,molecular,weights,ranging,from,kDa,which,are,mainly,extracted,sperm,cells,salmon,trout,Many,preclinical,studies,have,demonstrated,properties,These,include,inflammatory,apoptotic,osteoporotic,bone,regenerative,tissue,damage,preventive,ulcerative,wound,healing,mediated,by,activation,adenosine,A2A,receptor,salvage,pathways,Moreover,promotes,angiogenesis,cellular,activity,collagen,synthesis,soft,regeneration,priming,revitalization,can,be,used,treat,hyperpigmentation,Therefore,this,review,assessed,potential
AB值：
0.589752
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