首站-论文投稿智能助手
典型文献
A Feature Extraction Method for scRNA-seq Processing and Its Application on COVID-19 Data Analysis
文献摘要:
Single-cell RNA-sequencing (scRNA-seq) is a rapidly increasing research area in biomed-ical signal processing. However, the high complexity of single-cell data makes efficient and accurate analysis difficult. To improve the performance of single-cell RNA data processing, two single-cell features calculation method and corresponding dual-input neural network structures are proposed. In this feature extraction and fusion scheme, the features at the cluster level are extracted by hier-archical clustering and differential gene analysis, and the features at the cell level are extracted by the calculation of gene frequency and cross cell frequency. Our experiments on COVID-19 data demonstrate that the combined use of these two feature achieves great results and high robustness for classification tasks.
文献关键词:
作者姓名:
Xiumin Shi;Xiyuan Wu;Hengyu Qin
作者机构:
School of Information and Electronics, Beijing Institute of Technol-ogy, Beijing 100081, China
引用格式:
[1]Xiumin Shi;Xiyuan Wu;Hengyu Qin-.A Feature Extraction Method for scRNA-seq Processing and Its Application on COVID-19 Data Analysis)[J].北京理工大学学报(英文版),2022(03):285-292
A类:
B类:
Feature,Extraction,Method,scRNA,Processing,Its,Application,Data,Analysis,Single,cell,sequencing,rapidly,increasing,research,area,biomed,signal,processing,However,high,complexity,single,data,makes,efficient,accurate,analysis,difficult,To,improve,performance,features,calculation,method,corresponding,dual,input,neural,network,structures,proposed,In,this,extraction,fusion,scheme,level,extracted,by,hier,archical,clustering,differential,gene,frequency,cross,Our,experiments,demonstrate,that,combined,use,these,achieves,great,results,robustness,classification,tasks
AB值:
0.613043
相似文献
A Distributed Framework for Large-scale Protein-protein Interaction Data Analysis and Prediction Using MapReduce
Lun Hu-School of Computer Science and Technology, Dongguan University of Technology, Dongguan 523808,China;Xinjiang Technical Institute of Physics and Chemistry,Chinese Academy of Sciences, Urumqi 830000, China;School of Computer Science and Technology,Wuhan University of Technology, Wuhan 430070, China;Chongqing Engineering Research Center of Big Data Application for Smart Cities, and Chongqing Key Laboratory of Big Data and Intelligent Computing, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China;Center of Research Excellence in Renewable Energy and Power Systems, and the Department of Electrical and Computer Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia;Department of Electrical and Computer Engineering, New Jersey Institute of Technology, Newark, NJ 07102 USA
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。