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典型文献
New Anti-HSV-1 Guaiane Lactone from Hainan Gorgonian Echinomuricea indomalaccensis
文献摘要:
A new highly oxygenated guaiane lactone 5-epi-menverin C(1),along with four known compounds including one ses-quiterpene(2)and three steroids(3-5),were isolated from gorgonian Echinomuricea indomalaccensis which were collected from the South China Sea.Through anlyzing the NMR data and comparing with other reported compounds,their structures were determined.The absolute configuration of compound 1 was determined by comparing its experimental ECD with that obtained by calculation.In a bioassay in vitro,5-epi-menverin C(1)displayed antiviral activity against the HSV-1 virus with an inhibition rate of 69.2%(c=25μmol L-1).
文献关键词:
作者姓名:
ZHOU Lifan;CHEN Bao;ZHANG Yahui;ZHANG Xiuli;Li Xin;WANG Changyun
作者机构:
Key Laboratory of Marine Drugs,the Ministry of Education of China,School of Medicine and Pharmacy,Ocean University of China,Qingdao 266003,China;Laboratory for Marine Drugs and Bioproducts,Qingdao National Laboratory for Marine Science and Technology,Qingdao 266237,China;Institute of Evolution&Marine Biodiversity,Ocean University of China,Qingdao 266003,China
引用格式:
[1]ZHOU Lifan;CHEN Bao;ZHANG Yahui;ZHANG Xiuli;Li Xin;WANG Changyun-.New Anti-HSV-1 Guaiane Lactone from Hainan Gorgonian Echinomuricea indomalaccensis)[J].中国海洋大学学报(自然科学英文版),2022(04):965-968
A类:
Guaiane,Lactone,Gorgonian,Echinomuricea,indomalaccensis,menverin,quiterpene,gorgonian,anlyzing
B类:
New,Anti,HSV,from,Hainan,new,highly,oxygenated,guaiane,lactone,epi,along,four,known,compounds,including,ses,three,steroids,were,isolated,which,collected,South,China,Sea,Through,NMR,data,comparing,other,reported,their,structures,determined,absolute,configuration,was,by,its,experimental,ECD,that,obtained,calculation,In,bioassay,vitro,displayed,antiviral,activity,against,virus,inhibition,rate
AB值:
0.556939
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