典型文献
In vivo neuronal and astrocytic activation in somatosensory cortex by acupuncture stimuli
文献摘要：
Acupuncture is a medical treatment that has been widely practiced in China for over 3000 years, yet the neural mechanisms of acupuncture are not fully understood. We hypothesized that neurons and astrocytes act independently and synergistically under acupuncture stimulation. To investigate this, we used two-photon in vivo calcium recording to observe the effects of acupuncture stimulation at ST36 (Zusanli) in mice. Acupuncture stimulation in peripheral acupoints potentiated calcium signals of pyramidal neurons and astrocytes in the somatosensory cortex and resulted in late-onset calcium transients in astrocytes. Chemogenetic inhibition of neurons augmented the astrocytic activity. These findings suggest that acupuncture activates neuronal and astrocytic activity in the somatosensory cortex and provide evidence for the involvement of both neurons and astrocytes in acupuncture treatment.
文献关键词：
中图分类号：
作者姓名：
Xiao-Yue Chang;Kai Chen;Tong Cheng;Pui To Lai;Li Zhang;Kwok-Fai So;Edward S.Yang
作者机构：
Key Laboratory of CNS Regeneration(Minstry of Education),Guangdong-Hong Kong-Macau Institute of CNS Regeneration,Jinan University,Guangzhou,Guangdong Province,China;Department of Electrical and Electronic Engineering,The University of Hong Kong,Hong Kong Special Administrative Region,China;Center for Brain Science and Brain-InspiredIntelligence,Guangdong-Hong Kong-Macao Greater Bay Area,Guangzhou,Guangdong Province,China;Guangzhou Regenerative Medicine and Health Guangdong Laboratory,Guangzhou,Guangdong Province,China;State Key Laboratory of Brain and Cognitive Science,Li Ka Shing Faculty of Medicine,The University of Hong Kong,Hong Kong SpecialAdministrative Region,China
文献出处：
引用格式：
[1]Xiao-Yue Chang;Kai Chen;Tong Cheng;Pui To Lai;Li Zhang;Kwok-Fai So;Edward S.Yang-.In vivo neuronal and astrocytic activation in somatosensory cortex by acupuncture stimuli)[J].中国神经再生研究（英文版）,2022(11):2526-2529
A类：
Chemogenetic
B类：
In,vivo,neuronal,astrocytic,activation,somatosensory,cortex,by,acupuncture,stimuli,Acupuncture,medical,treatment,that,has,been,widely,practiced,China,over,years,yet,neural,mechanisms,are,not,fully,understood,We,hypothesized,neurons,astrocytes,independently,synergistically,stimulation,To,investigate,this,we,used,two,photon,calcium,recording,observe,effects,ST36,Zusanli,mice,peripheral,acupoints,potentiated,signals,pyramidal,resulted,late,onset,transients,inhibition,augmented,activity,These,findings,suggest,activates,provide,evidence,involvement,both
AB值：
0.571587
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
