典型文献
Emerging landscapes of nanosystems based on pre-metastatic microenvironment for cancer theranostics
文献摘要：
The emergence of disseminated metastasis is the leading cause of mortality in patients with malig-nant tumor.The pre-metastatic microenvironment,including the primary tumor-derived components,pre-metastatic niche(PMN),circulating tumor cells(CTCs),micro-metastases,and tumor immune mi-croenvironment(TIM),are the crucial factors to initiate metastasis and form macro-metastases.It may be a more promising strategy for directly targeting pre-metastatic microenvironment-interrelated fac-tors and cells before they have the chance to form secondary tumors to prevent metastasis.During re-cent years,a variety of nanosystems,with specific microstructures and functional properties,have been devised to selectively target pre-metastatic cells components and interrelated molecular,and exhibited strong potential on anti-metastatic therapy by absorbing and neutralizing primary tumor-derived compo-nents,preventing establishment of the PMN,eliminating the CTCs,eradicating the micro-metastases and modulating the TIM.In this review,we comprehensively review the emerging nanosystems based on the pre-metastatic microenvironments.Hopefully,this review can cast new lights for early preventing and attenuating metastatic progression.
文献关键词：
中图分类号：
作者姓名：
Yongchao Chu;Tao Sun;Chen Jiang
作者机构：
Key Laboratory of Smart Drug Delivery(Ministry of Education),Minhang Hospital,State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Institutes of Brain Science,Department of Pharmaceutics,School of Pharmacy,Research Center on Aging and Medicine,Fudan University,Shanghai 201203,China
文献出处：
引用格式：
[1]Yongchao Chu;Tao Sun;Chen Jiang-.Emerging landscapes of nanosystems based on pre-metastatic microenvironment for cancer theranostics)[J].中国化学快报（英文版）,2022(09):4157-4168
A类：
croenvironment
B类：
Emerging,landscapes,nanosystems,metastatic,cancer,theranostics,emergence,disseminated,metastasis,leading,cause,mortality,patients,malig,nant,including,primary,derived,components,niche,PMN,circulating,cells,CTCs,metastases,immune,TIM,are,crucial,factors,initiate,form,macro,It,may,more,promising,strategy,directly,targeting,interrelated,before,they,have,chance,secondary,tumors,During,cent,years,variety,specific,microstructures,functional,properties,been,devised,selectively,molecular,exhibited,strong,potential,anti,therapy,by,absorbing,neutralizing,preventing,establishment,eliminating,eradicating,modulating,In,this,review,we,comprehensively,emerging,microenvironments,Hopefully,cast,new,lights,early,attenuating,progression
AB值：
0.54381
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