A gold nanoparticle(AuNP)aggregation-induced colorimetric aptasensing method for quantitative detec-tion of sulfadimethoxine(SDM)with a smartphone was developed.AuNPs were complexed with aptamers which protected AuNPs from aggregating in high-concentration salt solutions.In the presence of SDM,SDM bound with the aptamer on the surface of AuNPs with higher affinity,which competitively des-orbed the aptamer from the AuNP surface and resulted in AuNPs aggregation,accompanied with a color change from red to purple-blue.The R,G and B values of images taken by a smartphone camera were analyzed with an app on the smartphone,and were utilized for quantitative analysis of SDM.Under the optimized conditions,the colorimetric aptasensing method using a smartphone showed high sensitivity for SDM,with the limit of detection of 0.023 ppm,lower than the allowed maximum SDM residue limit.This study provides a simple,fast,and easy to read method for on-site quantitative biochemical and cel-lular analysis.

Xiaoliang Zhang;Le Wang;Xiaochun Li;Xiujun Li

College of Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China;Department of Chemistry and Biochemistry,University of Texas at El Paso,El Paso,Texas 79968,United States

中国化学快报（英文版）

[1]Xiaoliang Zhang;Le Wang;Xiaochun Li;Xiujun Li-.AuNP aggregation-induced quantitative colorimetric aptasensing of sulfadimethoxine with a smartphone)[J].中国化学快报（英文版）,2022(06):3078-3082

aptasensing,sulfadimethoxine,orbed

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