典型文献
Pincer iridium(Ⅲ)-catalyzed enantioselective C(sp3)-H functionalization via carbenoid C-H insertion of 3-diazooxindoles with 1,4-cyclohexadiene
文献摘要：
The asymmetric carbenoid C-H insertion of 3-diazooxindoles into 1,4-cyclohexadiene has been accom-plished in the presence of chiral bis(imidazoline)NCN pincer iridium(Ⅲ)complexes as the catalysts.With a catalyst loading of 0.5 mol％,the reactions proceeded smoothly at 0℃to afford a variety of chiral 3-substituted oxindoles in good yields with moderate to excellent enantioselectivities(up to 99％ee).The protocol exhibits good functional group tolerance with respect to 3-diazooxindoles and is readily scaled up to 2 mmol scale without any loss in activity and enantioselectivity.Density functional theory(DFT)calculations have been performed to better understand the reaction mechanism and to explain the stere-ochemical outcome of the reactions.
文献关键词：
中图分类号：
作者姓名：
Nan Li;Xiaoyan Yang;Yanyan Zhu;Fang Wang;Junfang Gong;Maoping Song
作者机构：
College of Chemistry,Green Catalysis Center,Zhengzhou University,Zhengzhou 450001,China
文献出处：
引用格式：
[1]Nan Li;Xiaoyan Yang;Yanyan Zhu;Fang Wang;Junfang Gong;Maoping Song-.Pincer iridium(Ⅲ)-catalyzed enantioselective C(sp3)-H functionalization via carbenoid C-H insertion of 3-diazooxindoles with 1,4-cyclohexadiene)[J].中国化学快报（英文版）,2022(05):2437-2441
A类：
Pincer,carbenoid,diazooxindoles,cyclohexadiene,imidazoline,oxindoles,stere
B类：
iridium,catalyzed,enantioselective,sp3,functionalization,via,insertion,asymmetric,into,has,been,accom,plished,presence,chiral,bis,NCN,pincer,complexes,catalysts,With,loading,reactions,proceeded,smoothly,afford,variety,substituted,good,yields,moderate,excellent,enantioselectivities,protocol,exhibits,group,tolerance,respect,readily,scaled,without,any,loss,activity,enantioselectivity,Density,theory,DFT,calculations,have,performed,better,understand,mechanism,explain,ochemical,outcome
AB值：
0.553413
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