典型文献
CONTROL STRATEGIES FOR A TUMOR-IMMUNE SYSTEM WITH IMPULSIVE DRUG DELIVERY UNDER A RANDOM ENVIRONMENT
文献摘要：
This paper mainly studies the stochastic character of tumor growth in the pres-ence of immune response and periodically pulsed chemotherapy.First,a stochastic impulsive model describing the interaction and competition among normal cells,tumor cells and im-mune cells under periodically pulsed chemotherapy is established.Then,sufficient conditions for the extinction,non-persistence in the mean,weak and strong persistence in the mean of tumor cells are obtained.Finally,numerical simulations are performed which not only verify the theoretical results derived but also reveal some specific features.The results show that the growth trend of tumor cells is significantly affected by the intensity of noise and the frequency and dose of drug deliveries.In clinical practice,doctors can reduce the randomness of the environment and increase the intensity of drug input to inhibit the proliferation and growth of tumor cells.
文献关键词：
中图分类号：
作者姓名：
Mingzhan HUANG;Shouzong LIU;Xinyu SONG;Xiufen ZOU
作者机构：
College of Mathematics and Statistics,Xinyang Normal University,Xinyang 464000,China;School of Mathematics and Statistics,Computational Science Hubei Key Laboratory,Wuhan University,Wuhan 430072,China
文献出处：
引用格式：
[1]Mingzhan HUANG;Shouzong LIU;Xinyu SONG;Xiufen ZOU-.CONTROL STRATEGIES FOR A TUMOR-IMMUNE SYSTEM WITH IMPULSIVE DRUG DELIVERY UNDER A RANDOM ENVIRONMENT)[J].数学物理学报（英文版）,2022(03):1141-1159
A类：
STRATEGIES,TUMOR,IMMUNE,IMPULSIVE,DRUG,DELIVERY,UNDER,RANDOM,ENVIRONMENT
B类：
CONTROL,FOR,SYSTEM,WITH,This,paper,mainly,studies,stochastic,character,tumor,growth,pres,immune,response,periodically,pulsed,chemotherapy,First,impulsive,model,describing,interaction,competition,among,normal,cells,under,established,Then,sufficient,conditions,extinction,persistence,mean,weak,strong,are,obtained,Finally,numerical,simulations,performed,which,not,only,verify,theoretical,results,derived,but,also,reveal,some,specific,features,show,that,trend,significantly,affected,by,intensity,noise,frequency,dose,drug,deliveries,In,clinical,practice,doctors,reduce,randomness,environment,increase,input,inhibit,proliferation
AB值：
0.567793
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